Nordihydroguaiaretic acid

• Catalog No.: N5023
• CAS Number: 500-38-9
• M. F.: C18H22O4
• M. W.: 302.36488
• Purity: ≥90% (HPLC)

SYNONYMS

• Title: 去甲二氢愈创木酸
• IUPAC name: 4-{3-[(3,4-dihydroxyphenyl)methyl]-2-methylbutyl}benzene-1,2-diol
• IUPAC Traditional name: nordihydroguaiaretic acid
• Synonyms: NDGA; 4,4′-(2,3-二甲基四亚甲基)二邻苯二酚; 1,4-双(3,4-二羟苯基)-2,3-二甲基丁烷; 马索罗酚

DATABASE IDS

• CAS Number: 500-38-9
• MDL Number: MFCD00002206
• PubChem SID: 24278590
• EC Number: 207-903-0
• Beilstein Number: 2056826

PROPERTIES

• Biological Source: from Larrea divaricata (creosote bush)
• Purity: ≥90% (HPLC)
• Gene Information: human ... ALOX15(246), PTGS1(5742), PTGS2(5743)mouse ... Alox12(11684)
• Melting Point: 184-186 °C(lit.)
• GHS Signal Word: Warning
• GHS Hazard statements: H302-H315-H319-H335
• European Hazard Symbols: Harmful (Xn)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• GHS Precautionary statements: P261-P305 + P351 + P338
• Risk Statements: 22-36/37/38
• RTECS: UX1750000
• Safety Statements: 26-36/37
• German water hazard class: 3

DETAILS

Description (简体中文)

Biochem/physiol Actions
脂氧合酶抑制剂；含多酚的邻二羟基（儿茶酚）结构。