Amikacin sulfate salt

• Catalog No.: A2324
• CAS Number: 149022-22-0
• M. F.: C22H45N5O17S
• M. W.: 683.681

SYNONYMS

• IUPAC name: (2R)-4-amino-N-[(1R,2S,3S,4R,5S)-5-amino-2-{[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-4-{[(2R,3R,4S,5S,6R)-6-(aminomethyl)-3,4,5-trihydroxyoxan-2-yl]oxy}-3-hydroxycyclohexyl]-2-hydroxybutanamide; sulfuric acid
• IUPAC Traditional name: (2R)-4-amino-N-[(1R,2S,3S,4R,5S)-5-amino-2-{[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-4-{[(2R,3R,4S,5S,6R)-6-(aminomethyl)-3,4,5-trihydroxyoxan-2-yl]oxy}-3-hydroxycyclohexyl]-2-hydroxybutanamide; sulfuric acid

DATABASE IDS

• MDL Number: MFCD00167477
• PubChem SID: 24890648
• CAS Number: 149022-22-0

PROPERTIES

• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• RTECS: WK1961200
• Storage Temperature: 2-8°C
• German water hazard class: 2

DETAILS

Description (English)

Biochem/physiol Actions
Antibacterial spectrum: Gram-negative and gram-positive bacteria.
Amikacin prevents bacterial protein synthesis by binding to the 30S ribosome subunit and inducing mRNA misreading.
Other Notes
Aminoglycoside antibiotic. Derivative of kanamycin.
Quality
Amikacin:Sulfate ratio 1:1.8
Application
Amikacin is an aminoglycoside antibiotic commonly used in the treatment of drug-resistant mycobacteria 1. It is used to study organism-directed delivery of antibiotics as well as drug resistance 2.