Thiostrepton from Streptomyces azureus

• Catalog No.: T8902
• CAS Number: 1393-48-2
• M. F.: C72H85N19O18S5
• M. W.: 1664.8868
• Purity: ≥90% (HPLC)

SYNONYMS

• IUPAC name: 2-({2-[(11Z)-37-(butan-2-yl)-18-(2,3-dihydroxybutan-2-yl)-11-ethylidene-59-hydroxy-8,60-bis(1-hydroxyethyl)-26,40,46-trimethyl-43-methylidene-6,9,16,23,28,38,41,44,47-nonaoxo-27-oxa-3,13,20,56-tetrathia-7,10,17,24,30,36,39,42,45,48,52,58,62,63,64-pentadecaazanonacyclo[23.23.9.2^2^9,^3^2.1^2,^5.1^1^2,^1^5.1^1^9,^2^2.1^3^1,^3^5.1^5^4,^5^7.0^1,^5^3]tetrahexaconta-2(64),4,12(63),19(62),21,29(61),30,32(60),33,51,54,57-dodecaen-51-yl]-1,3-thiazol-4-yl}formamido)-N-(1-carbamoyleth-1-en-1-yl)prop-2-enamide
• IUPAC Traditional name: N-(1-carbamoyleth-1-en-1-yl)-2-({2-[(11Z)-18-(2,3-dihydroxybutan-2-yl)-11-ethylidene-59-hydroxy-8,60-bis(1-hydroxyethyl)-26,40,46-trimethyl-43-methylidene-6,9,16,23,28,38,41,44,47-nonaoxo-37-(sec-butyl)-27-oxa-3,13,20,56-tetrathia-7,10,17,24,30,36,39,42,45,48,52,58,62,63,64-pentadecaazanonacyclo[23.23.9.2^2^9,^3^2.1^2,^5.1^1^2,^1^5.1^1^9,^2^2.1^3^1,^3^5.1^5^4,^5^7.0^1,^5^3]tetrahexaconta-2(64),4,12(63),19(62),21,29(61),30,32(60),33,51,54,57-dodecaen-51-yl]-1,3-thiazol-4-yl}formamido)prop-2-enamide

DATABASE IDS

• MDL Number: MFCD00135828
• EC Number: 215-734-9
• CAS Number: 1393-48-2
• PubChem SID: 24900569

PROPERTIES

• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• RTECS: XN6300100
• Storage Temperature: -20°C
• German water hazard class: 3
• GHS Signal Word: Warning
• GHS Hazard statements: H302
• Purity: ≥90% (HPLC)

DETAILS

Description (English)

Biochem/physiol Actions
Peptide antibiotic that prevents the binding of elongation factor G (EF-G) and GTP to the 50S ribosomal subunit.