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Lincomycin hydrochloride_Molecular_structure_CAS_859-18-7)
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Lincomycin hydrochloride

Catalog No. L6004 Name Sigma Aldrich
CAS Number 859-18-7 Website http://www.sigmaaldrich.com
M. F. C18H35ClN2O6S Telephone 1-800-521-8956
M. W. 442.9983 Fax
Purity ≥90% (TLC) Email
Storage Chembase ID: 132521


Lincomycin hydrochloride 盐酸盐
IUPAC name
(2S,4R)-N-[(1R,2R)-2-hydroxy-1-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(methylsulfanyl)oxan-2-yl]propyl]-1-methyl-4-propylpyrrolidine-2-carboxamide hydrochloride
IUPAC Traditional name
lincomycin hydrochloride
Methyl 6,8-dideoxy-6-(1-methyl-4-propyl-2-pyrrolidinecarboxamido)-1-thio-D-erythro-α-D-galactooctopyranoside 盐酸盐
Lincocin 盐酸盐


Beilstein Number 4171650
EC Number 212-726-7
MDL Number MFCD00083647
CAS Number 859-18-7


Potency 800-900 units per mg
Purity ≥90% (TLC)
GHS Pictograms GHS07
GHS Signal Word Warning
GHS Hazard statements H315-H319-H335
European Hazard Symbols Irritant Irritant (Xi)
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
GHS Precautionary statements P261-P305 + P351 + P338
Risk Statements 36/37/38
RTECS RH6315000
Safety Statements 26
Storage Temperature 2-8°C
German water hazard class 2


Description (English)
Biochem/physiol Actions
Lincomycin is a lincosamide antibiotic that forms cross-links within the peptidyl transferase loop region of the 23S rRNA.3Mode of action: inhibits bacterial protein synthesis Antimicrobial spectrum: Gram-positive bacteria
Lincomycin hydrochloride is an antibiotic used to study the inhibition of protein synthesis, bacterial antibiotic resistance, and protein and surfactant binding 1,2 Product L6004 is ≥90% (TLC). It is produced by Streptomyces lincolnensis var. lincolnensis and has been used in the treatment of Staphylococcal, Streptococcal, and Bacteroides fragilis infections.
Protocols & Applications
Antibiotic Selector for application, solubility, solution stability, working concentration, and mode of action information