Lincomycin hydrochloride

• Catalog No.: L6004
• CAS Number: 859-18-7
• M. F.: C18H35ClN2O6S
• M. W.: 442.9983
• Purity: ≥90% (TLC)

SYNONYMS

• Title: Lincomycin hydrochloride 盐酸盐
• IUPAC name: (2S,4R)-N-[(1R,2R)-2-hydroxy-1-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(methylsulfanyl)oxan-2-yl]propyl]-1-methyl-4-propylpyrrolidine-2-carboxamide hydrochloride
• IUPAC Traditional name: lincomycin hydrochloride
• Synonyms: Methyl 6,8-dideoxy-6-(1-methyl-4-propyl-2-pyrrolidinecarboxamido)-1-thio-D-erythro-α-D-galactooctopyranoside 盐酸盐; Lincocin 盐酸盐

DATABASE IDS

• Beilstein Number: 4171650
• EC Number: 212-726-7
• MDL Number: MFCD00083647
• CAS Number: 859-18-7

PROPERTIES

• Potency: 800-900 units per mg
• Purity: ≥90% (TLC)
• GHS Signal Word: Warning
• GHS Hazard statements: H315-H319-H335
• European Hazard Symbols: Irritant (Xi)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• GHS Precautionary statements: P261-P305 + P351 + P338
• Risk Statements: 36/37/38
• RTECS: RH6315000
• Safety Statements: 26
• Storage Temperature: 2-8°C
• German water hazard class: 2

DETAILS

Description (English)

Biochem/physiol Actions
Lincomycin is a lincosamide antibiotic that forms cross-links within the peptidyl transferase loop region of the 23S rRNA.3Mode of action: inhibits bacterial protein synthesis Antimicrobial spectrum: Gram-positive bacteria
Application
Lincomycin hydrochloride is an antibiotic used to study the inhibition of protein synthesis, bacterial antibiotic resistance, and protein and surfactant binding 1,2 Product L6004 is ≥90% (TLC). It is produced by Streptomyces lincolnensis var. lincolnensis and has been used in the treatment of Staphylococcal, Streptococcal, and Bacteroides fragilis infections.
Protocols & Applications
Antibiotic Selector for application, solubility, solution stability, working concentration, and mode of action information