Doxycycline hyclate

• Catalog No.: D9891
• CAS Number: 24390-14-5
• M. F.: C46H58Cl2N4O18
• M. W.: 1025.87472
• Purity: ≥98% (TLC)

SYNONYMS

• Title: 多西环素 单盐酸半乙醇半水合物
• IUPAC name: bis((4S,5S,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide) ethanol hydrate dihydrochloride
• IUPAC Traditional name: bis((4S,5S,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide) ethyl alcohol hydrate dihydrochloride
• Synonyms: 多西环素盐酸盐半乙醇化物半水合物

DATABASE IDS

• PubChem SID: 24278399
• MDL Number: MFCD07357237
• CAS Number: 24390-14-5
• Beilstein Number: 5702728

PROPERTIES

• Purity: ≥98% (TLC)
• Solubility: Do you have solubility information on this product that you would like to share?
• GHS Signal Word: Warning
• GHS Hazard statements: H302-H315-H319-H335
• European Hazard Symbols: Harmful (Xn)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• GHS Precautionary statements: P261-P305 + P351 + P338
• Risk Statements: 22-36/37/38
• RTECS: QI8925000
• Safety Statements: 26
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (English)

Frequently Asked Questions
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Application
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Doxycycline hyclate is a synthetic oxytetracycline derivative. It has been used to eliminate Borrelia burgdorferi and Anaplasma phagocytophilum in rodent reservoirs and to eliminate Ixodes scapularis ticks1. It is used to inhibit matrix metalloproteinases2 and has been used to inhibit the inflammatory response of Lyme Disease3.
Biochem/physiol Actions
Derivative of oxytetracycline. A broad spectrum inhibitor used to inhibit matrix metallo-proteinases (MMP) such as type 1 collagenase in studies on would healing and tissue remodeling.
Doxycycline hyclate inhibits the inflammatory response to the Lyme Disease Spirochete Borrelia burgdorferi3. It is a broad spectrum inhibitor of matrix metalloproteinases in vivo.
Protocols & Applications
Antibiotic Selector for application, solubility, solution stability, working concentration, and mode of action information