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Nogalamycin

Catalog No. N2019 Name Sigma Aldrich
CAS Number 1404-15-5 Website http://www.sigmaaldrich.com
M. F. C39H49NO16 Telephone 1-800-521-8956
M. W. 787.80346 Fax
Purity ≥95% Email
Storage Chembase ID: 132488

SYNONYMS

IUPAC name
methyl 23-(dimethylamino)-4,8,12,22,24-pentahydroxy-1,12-dimethyl-6,17-dioxo-10-[(3,4,5-trimethoxy-4,6-dimethyloxan-2-yl)oxy]-20,25-dioxahexacyclo[19.3.1.02,19.05,18.07,16.09,14]pentacosa-2(19),3,5(18),7,9(14),15-hexaene-13-carboxylate
IUPAC Traditional name
methyl 23-(dimethylamino)-4,8,12,22,24-pentahydroxy-1,12-dimethyl-6,17-dioxo-10-[(3,4,5-trimethoxy-4,6-dimethyloxan-2-yl)oxy]-20,25-dioxahexacyclo[19.3.1.02,19.05,18.07,16.09,14]pentacosa-2(19),3,5(18),7,9(14),15-hexaene-13-carboxylate

DATABASE IDS

PubChem SID 24897545
MDL Number MFCD00083442
CAS Number 1404-15-5

PROPERTIES

Purity ≥95%
Biological Source from Streptomyces nogalater
GHS Pictograms GHS07
GHS Pictograms GHS08
GHS Signal Word Danger
GHS Hazard statements H302-H312-H332-H350-H360
European Hazard Symbols Toxic Toxic (T)
Personal Protective Equipment Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
GHS Precautionary statements P201-P280-P308 + P313
Risk Statements 45-46-61-20/21/22
RTECS RA4550000
Safety Statements 53-22-36/37/39-45
Storage Temperature 2-8°C
German water hazard class 3

DETAILS

Description (English)
Biochem/physiol Actions
Anthracyclic antitumor antibiotic. It is used as a sequence specific DNA binding (intercalation) reagent, binds d(CGTACG), d(ATGCAT).
Anthracyclic antitumor antibiotic.

REFERENCES