D-Cycloserine

• Catalog No.: C6880
• CAS Number: 68-41-7
• M. F.: C3H6N2O2
• M. W.: 102.09194

SYNONYMS

• Title: D-环丝氨酸
• IUPAC name: (4R)-4-amino-1,2-oxazolidin-3-one
• IUPAC Traditional name: cycloserine
• Synonyms: 4-氨基-3-异噁唑烷酮; (R)-4-氨基-3-异噁唑烷酮

DATABASE IDS

• MDL Number: MFCD00005353
• CAS Number: 68-41-7
• PubChem SID: 24892907
• Beilstein Number: 80798
• EC Number: 200-688-4

PROPERTIES

• Gene Information: human ... GRIN1(2902), GRIN2A(2903), GRIN2B(2904), GRIN2C(2905), GRIN2D(2906), GRIN3A(116443), GRIN3B(116444), GRINA(2907)mouse ... GRIN1(14810), GRIN2A(14811), GRIN2B(14812), GRIN2C(14813), GRIN2D(14814), GRIN3A(242443), GRIN3B(170483), GRINA(66168)rat ... GRIN1(24408), GRIN2A(24409), GRIN2B(24410), GRIN2C(24411), GRIN2D(24412), GRIN3A(191573), GRIN3B(170796), GRINA(266668)
• Apperance: powder
• Melting Point: 147 °C (dec.)(lit.)
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• RTECS: NY2975000
• Storage Temperature: -20°C
• German water hazard class: 2

DETAILS

Description (简体中文)

Biochem/physiol Actions
Partial agonist at the glycine modulatory site of NMDA glutamatergic receptors; antibiotic against Gram-negative bacteria.
作用方式：抑制细胞壁的生物合成（D-Ala 肽键的形成）。也会阻碍 D-Ala 向 L-Ala 的转化。抑菌。 抗性机理：干扰 D-Ala 转运。
包装
1, 5 g in poly bottle