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Amikacin hydrate

Catalog No. A3650 Name Sigma Aldrich
CAS Number 37517-28-5(anhydrous) Website http://www.sigmaaldrich.com
M. F. C22H45N5O14 Telephone 1-800-521-8956
M. W. 603.6178 Fax
Purity Email
Storage Chembase ID: 132448

SYNONYMS

IUPAC name
(2S)-4-amino-N-[(1R,2S,3S,4R,5S)-5-amino-2-{[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-4-{[(2R,3R,4S,5S,6R)-6-(aminomethyl)-3,4,5-trihydroxyoxan-2-yl]oxy}-3-hydroxycyclohexyl]-2-hydroxybutanamide hydrate
IUPAC Traditional name
amikacin hydrate
Synonyms
N1-[(S)-4-Amino-2-hydroxybutyryl]kanamycin A

DATABASE IDS

CAS Number 37517-28-5(anhydrous)
Beilstein Number 1445422
EC Number 253-538-5
MDL Number MFCD11045969
PubChem SID 24890796

PROPERTIES

Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
RTECS WK1955000
Storage Temperature 2-8°C
German water hazard class 2

DETAILS

Description (English)
Application
Amikacin hydrate is used in antimicrobial susceptibility studies of organisms such as Mycobacterium tuberculosis1and Ehrlichia phagocytophila.2
Biochem/physiol Actions
Amikacin prevents bacterial protein synthesis by binding to the 30S ribosome subunit and inducing mRNA misreading.

REFERENCES