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Galanin human

Catalog No. G0278 Name Sigma Aldrich
CAS Number 119418-04-1 Website http://www.sigmaaldrich.com
M. F. C139H210N42O43 Telephone 1-800-521-8956
M. W. 3157.4103 Fax
Purity ≥97% (HPLC) Email
Storage Chembase ID: 132438

SYNONYMS

IUPAC name
(3S)-3-{[(1S)-5-amino-1-{[(1S)-2-carbamoyl-1-[({[(1S)-1-{[(1S,2R)-1-{[(1S)-1-carboxy-2-hydroxyethyl]carbamoyl}-2-hydroxypropyl]carbamoyl}-3-methylbutyl]carbamoyl}methyl)carbamoyl]ethyl]carbamoyl}pentyl]carbamoyl}-3-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-{2-[(2S)-2-[(2S)-2-[(2S)-2-{[(2S)-1-{2-[(2S)-2-[(2S)-2-[(2S)-2-{2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S,3R)-2-[(2S)-2-(2-aminoacetamido)-3-(1H-indol-3-yl)propanamido]-3-hydroxybutanamido]-4-methylpentanamido]-3-carbamoylpropanamido]-3-hydroxypropanamido]propanamido]acetamido}-3-(4-hydroxyphenyl)propanamido]-4-methylpentanamido]-4-methylpentanamido]acetyl}pyrrolidin-2-yl]formamido}-3-(1H-imidazol-4-yl)propanamido]propanamido]-3-methylbutanamido]acetamido}-3-carbamoylpropanamido]-3-(1H-imidazol-4-yl)propanamido]-5-carbamimidamidopentanamido]-3-hydroxypropanamido]-3-phenylpropanamido]-3-hydroxypropanamido]propanoic acid
IUPAC Traditional name
(3S)-3-{[(1S)-5-amino-1-{[(1S)-2-carbamoyl-1-[({[(1S)-1-{[(1S,2R)-1-{[(1S)-1-carboxy-2-hydroxyethyl]carbamoyl}-2-hydroxypropyl]carbamoyl}-3-methylbutyl]carbamoyl}methyl)carbamoyl]ethyl]carbamoyl}pentyl]carbamoyl}-3-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-{2-[(2S)-2-[(2S)-2-[(2S)-2-{[(2S)-1-{2-[(2S)-2-[(2S)-2-[(2S)-2-{2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S,3R)-2-[(2S)-2-(2-aminoacetamido)-3-(1H-indol-3-yl)propanamido]-3-hydroxybutanamido]-4-methylpentanamido]-3-carbamoylpropanamido]-3-hydroxypropanamido]propanamido]acetamido}-3-(4-hydroxyphenyl)propanamido]-4-methylpentanamido]-4-methylpentanamido]acetyl}pyrrolidin-2-yl]formamido}-3-(1H-imidazol-4-yl)propanamido]propanamido]-3-methylbutanamido]acetamido}-3-carbamoylpropanamido]-3-(1H-imidazol-4-yl)propanamido]-5-carbamimidamidopentanamido]-3-hydroxypropanamido]-3-phenylpropanamido]-3-hydroxypropanamido]propanoic acid

DATABASE IDS

CAS Number 119418-04-1
MDL Number MFCD00135986

PROPERTIES

Compostion Peptide content, ≥70%
Purity ≥97% (HPLC)
Gene Information human ... GAL(51083)
Apperance powder
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Storage Temperature -20°C
German water hazard class 3

DETAILS

Description (English)
Amino Acid Sequence
Gly-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-Gly-Pro-His-Ala-Val-Gly-Asn-His-Arg-Ser-Phe-Ser-Asp-Lys-Asn-Gly-Leu-Thr-Ser
Biochem/physiol Actions
Co-localized with acetylcholine and inhibits its release; inhibits the release of glutamic acid, decreases excitability of spinal neurons; blocks voltage-activated Ca2+ channels; linked to behavioral and cognitive deficits in Alzheimer′s disease.

REFERENCES