Mycophenolic acid

• Catalog No.: M3536
• CAS Number: 24280-93-1
• M. F.: C17H20O6
• M. W.: 320.3371
• Purity: ≥98%

SYNONYMS

• IUPAC name: (4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-4-methylhex-4-enoic acid
• IUPAC Traditional name: mycophenolic acid
• Synonyms: 6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoic acid; NSC 129185; 6-(1,3-Dihydro-7-hydroxy-5-methoxy-4-methyl-1-oxoisobenzofuran-6-yl)-4-methyl-4-hexanoic acid

DATABASE IDS

• MDL Number: MFCD00036814
• EC Number: 246-119-3
• CAS Number: 24280-93-1
• Beilstein Number: 1295848
• PubChem SID: 24896854

PROPERTIES

• Personal Protective Equipment: Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
• GHS Signal Word: Danger
• GHS Hazard statements: H302-H341-H360D-H372-H410
• European Hazard Symbols: Toxic (T)
• European Hazard Symbols: Nature polluting (N)
• GHS Precautionary statements: P201-P273-P281-P308 + P313-P501
• Risk Statements: 61-22-48/25-50/53-68
• RTECS: MP8050000
• Safety Statements: 53-22-45-61
• Storage Temperature: 2-8°C
• German water hazard class: 3
• Purity: ≥98%
• Quality Level: PREMIUM
• Suitability: suitable for cell culture
• Gene Information: human ... IMPDH1(3614), IMPDH2(3615)
• Target Organ: Immune system
• Apperance: powder
• Solubility: methanol: soluble50 mg/mL

DETAILS

Description (English)

Application
Recommended for use as a selection agent at 25 μg/ml.
Used to select animal cells expressing the Escherichia coli gene for xanthine-guanine phosphosribosyl transferase.
Biochem/physiol Actions
Immunosuppressive agent. Suppresses cytokine-induced nitric oxide production.
Immunosuppressive agent. Used to inhibit early stage biosynthesis of purine nucleotides. Used as a specific inhibitor of inosine 5′-monophosphate (IMP) dehydrogenase (IMPDH) and inducer of IMP dehydrogenase gene expression.
Protocols & Applications
Antibiotic Selector for application, solubility, solution stability, working concentration, and mode of action information