8-Bromoadenosine 3′,5′-cyclic monophosphate sodium salt

• Catalog No.: B7880
• CAS Number: 76939-46-3
• M. F.: C10H10BrN5NaO6P
• M. W.: 430.083831
• Purity: ≥97% (HPLC)

SYNONYMS

• IUPAC name: sodium (4aR,6R,7R,7aS)-6-(6-amino-8-bromo-9H-purin-9-yl)-7-hydroxy-2-oxo-hexahydro-1,3,5,2λ^5-furo[3,2-d][1,3,2λ^5]dioxaphosphinin-2-olate
• IUPAC Traditional name: sodium (4aR,6R,7R,7aS)-6-(6-amino-8-bromopurin-9-yl)-7-hydroxy-2-oxo-tetrahydro-4H-1,3,5,2λ^5-furo[3,2-d][1,3,2λ^5]dioxaphosphinin-2-olate
• Synonyms: 8-Br-cAMP

DATABASE IDS

• Beilstein Number: 7739743
• CAS Number: 76939-46-3
• MDL Number: MFCD00005844
• PubChem SID: 24278020

PROPERTIES

• Purity: ≥97% (HPLC)
• Apperance: off-white powder
• Solubility: H2O: soluble100 mg/mL
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• Storage Temperature: -20°C
• German water hazard class: 3

DETAILS

Description (English)

Caution
Sensitive to light and moisture.
Other Notes
Membrane-permeable cAMP analog.
Biochem/physiol Actions
Cell-permeable cAMP analog having greater resistance to hydrolysis by phosphodiesterases than cAMP. Activates protein kinase A, inhibits growth, decreases proliferation, increases differentiation, and induces apoptosis of cultured cells.