Carbonyl cyanide 4-(trifluoromethoxy)phenylhydrazone

• Catalog No.: C2920
• CAS Number: 370-86-5
• M. F.: C10H5F3N4O
• M. W.: 254.1681096
• Purity: ≥98% (TLC)

SYNONYMS

• Title: 碳酰氰 4-(三氟甲氧基)苯腙
• IUPAC name: 1-cyano-N-[4-(trifluoromethoxy)phenyl]methanecarbohydrazonoyl cyanide
• IUPAC Traditional name: 1-cyano-N-[4-(trifluoromethoxy)phenyl]methanecarbohydrazonoyl cyanide
• Synonyms: 羰基氰对三氟甲氧基苯腙; FCCP

DATABASE IDS

• PubChem SID: 24892549
• Beilstein Number: 664446
• MDL Number: MFCD00009699
• CAS Number: 370-86-5
• EC Number: 206-730-8

PROPERTIES

• Purity: ≥98% (TLC)
• Quality Level: PREMIUM
• Apperance: yellow powder
• Melting Point: 174-175 °C (dec.)(lit.)
• Solubility: 95% ethanol: soluble
• GHS Signal Word: Danger
• GHS Hazard statements: H301-H317-H413
• European Hazard Symbols: Toxic (T)
• Personal Protective Equipment: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
• GHS Precautionary statements: P280-P301 + P310
• RID/ADR: UN 2811 6.1/PG 2
• Risk Statements: 25-43
• RTECS: FG5775000
• Safety Statements: 36/37-45
• Storage Temperature: 2-8°C
• Hazard Class: 6.1
• UN Number: 2811
• Packing Group: 2
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
FCCP is a protonophore (H+ ionophore) and uncoupler of oxidative phosphorylation in mitochondria. It is capable of depolarizing plasma and mitochondrial membranes. FCCP has been shown to have a number of effects on cellular calcium. It also is reported to inhibit a background K+ current and induce a small inward current, reduce pH by 0.1 unit, and induce a rise of intracellular [Na+]. FCCP stimulates Mg2+-ATPase activity, inhibits β-amyloid production, and mimics the effect of selective glutamate agonist N-methyl-D-aspartate (NMDA) on mitochondrial superoxide production.