6-Biopterin

• Catalog No.: B2517
• CAS Number: 22150-76-1
• M. F.: C9H11N5O3
• M. W.: 237.21534
• Purity: ≥97%

SYNONYMS

• IUPAC name: 2-amino-6-[(1R,2S)-1,2-dihydroxypropyl]-1,4-dihydropteridin-4-one
• IUPAC Traditional name: 2-amino-6-[(1R,2S)-1,2-dihydroxypropyl]-1H-pteridin-4-one
• Synonyms: (1’R,2’S)-Biopterin; 2-Amino-4-hydroxy-6-(1,2-dihydroxypropyl)pteridine; L-erythro-6-(1,2-Dihydroxypropyl)pterin

DATABASE IDS

• EC Number: 244-807-8
• CAS Number: 22150-76-1
• Beilstein Number: 87860
• PubChem SID: 24891654
• MDL Number: MFCD00036787

PROPERTIES

• Purity: ≥97%
• GHS Signal Word: Warning
• GHS Hazard statements: H315-H319-H335
• European Hazard Symbols: Irritant (Xi)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• GHS Precautionary statements: P261-P305 + P351 + P338
• Risk Statements: 36/37/38
• RTECS: UO3506000
• Safety Statements: 26-36
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (English)

Application
6-Biopterin is an oxidation product from the melanogenesis regulating cofactor (6R)5,6,7,8 tetrahydrobiopterin (6-BH4). In vitro, 6-Biopterin is cytotoxic to melanocytes. However, in vivo, 6-Biopterin is rapidly and sequentially reduced back to 6-GH4 via q-BH2. Recent studies suggest that 6-Biopterin among other pteridines may be a useful non-invasive biomarker for cancer.