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6-Biopterin

Catalog No. B2517 Name Sigma Aldrich
CAS Number 22150-76-1 Website http://www.sigmaaldrich.com
M. F. C9H11N5O3 Telephone 1-800-521-8956
M. W. 237.21534 Fax
Purity ≥97% Email
Storage Chembase ID: 126161

SYNONYMS

IUPAC name
2-amino-6-[(1R,2S)-1,2-dihydroxypropyl]-1,4-dihydropteridin-4-one
IUPAC Traditional name
2-amino-6-[(1R,2S)-1,2-dihydroxypropyl]-1H-pteridin-4-one
Synonyms
(1’R,2’S)-Biopterin
2-Amino-4-hydroxy-6-(1,2-dihydroxypropyl)pteridine
L-erythro-6-(1,2-Dihydroxypropyl)pterin

DATABASE IDS

EC Number 244-807-8
CAS Number 22150-76-1
Beilstein Number 87860
PubChem SID 24891654
MDL Number MFCD00036787

PROPERTIES

Purity ≥97%
GHS Pictograms GHS07
GHS Signal Word Warning
GHS Hazard statements H315-H319-H335
European Hazard Symbols Irritant Irritant (Xi)
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
GHS Precautionary statements P261-P305 + P351 + P338
Risk Statements 36/37/38
RTECS UO3506000
Safety Statements 26-36
Storage Temperature 2-8°C
German water hazard class 3

DETAILS

Description (English)
Application
6-Biopterin is an oxidation product from the melanogenesis regulating cofactor (6R)5,6,7,8 tetrahydrobiopterin (6-BH4). In vitro, 6-Biopterin is cytotoxic to melanocytes. However, in vivo, 6-Biopterin is rapidly and sequentially reduced back to 6-GH4 via q-BH2. Recent studies suggest that 6-Biopterin among other pteridines may be a useful non-invasive biomarker for cancer.

REFERENCES