5-Bromo-2′-deoxyuridine

• Catalog No.: B5002
• CAS Number: 59-14-3
• M. F.: C9H11BrN2O5
• M. W.: 307.09804
• Purity: ≥99% (HPLC)

SYNONYMS

• Title: 5-溴-2′-脱氧尿苷
• IUPAC name: 5-bromo-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione
• IUPAC Traditional name: 5-bromo-2'-deoxyuridine
• Synonyms: 5-BrdU; 5-溴-1-(2-脱氧-β-D-呋喃核糖)尿嘧啶; BUdR; 5-溴脱氧尿苷

DATABASE IDS

• MDL Number: MFCD00006529
• Beilstein Number: 30395
• PubChem SID: 24278270
• CAS Number: 59-14-3
• EC Number: 200-415-9

PROPERTIES

• Purity: ≥99% (HPLC)
• Melting Point: 191-194 °C (dec.)(lit.)
• GHS Signal Word: Danger
• GHS Hazard statements: H340-H361
• European Hazard Symbols: Toxic (T)
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• GHS Precautionary statements: P201-P281-P308 + P313
• Risk Statements: 46-61
• RTECS: YU7350000
• Safety Statements: 53-45
• Storage Temperature: -20°C
• German water hazard class: 2

DETAILS

Description (简体中文)

Frequently Asked Questions
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Biochem/physiol Actions
用作遗传研究中诱变剂的胸苷类似物。在 S 期可选择性结合到细胞 DNA 中。
包装
1, 5, 100 g in glass bottle
100, 250, 500 mg in glass bottle
Application
5-Bromo-2′-deoxyuridine (5-BrdU) is a thymidine analogue which is incorporated into DNA. 5-BrdU is routinely and extensively used to measure DNA synthesis and to label dividing cells. Consequently 5-BrdU is used to study cell signaling and other processes that induce cell proliferation.