Retinoic acid

• Catalog No.: R2625
• CAS Number: 302-79-4
• M. F.: C20H28O2
• M. W.: 300.43512
• Purity: ≥98% (HPLC)

SYNONYMS

• IUPAC name: (2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid
• IUPAC Traditional name: tretinoin
• Synonyms: tretinoin; ATRA; all-trans-Retinoic acid; Vitamin A acid

DATABASE IDS

• EC Number: 206-129-0
• PubChem SID: 24278674
• MDL Number: MFCD00001551
• CAS Number: 302-79-4
• Beilstein Number: 2057223

PROPERTIES

• Purity: ≥98% (HPLC)
• Gene Information: human ... RARA(5914), RARB(5915), RARG(5916), RXRA(6256), RXRB(6257), RXRG(6258)mouse ... Rara(19401), Rarb(218772), Rarg(19411), Rxrb(20182)
• Apperance: yellow powder
• Melting Point: 180-181 °C(lit.)
• GHS Signal Word: Warning
• GHS Hazard statements: H302
• European Hazard Symbols: Harmful (Xn)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• Risk Statements: 22
• RTECS: VH6475000
• Safety Statements: 61
• Storage Temperature: -20°C
• German water hazard class: 2

DETAILS

Description (简体中文)

Frequently Asked Questions
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包装
1, 5 g in ampule
50, 100, 500 mg in ampule
Sealed ampule
Biochem/physiol Actions
all-trans-Retinoic acid (ATRA) is a ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR). The bound RAR and RXR act as transcription factors that regulate the growth and differentiation of both normal and malignant cells. Cytochromes P450 (CYPs) catalyze the 4-hydroxylation of ATRA. Retinoic acid primes embryonic stem cells to become neurons.
Other Notes
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. R2625.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.