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Rotenone

Catalog No. R8875 Name Sigma Aldrich
CAS Number 83-79-4 Website http://www.sigmaaldrich.com
M. F. C23H22O6 Telephone 1-800-521-8956
M. W. 394.41718 Fax
Purity ≥95% Email
Storage Chembase ID: 119518

SYNONYMS

Title
鱼滕精
IUPAC name
(1S,6R,13S)-16,17-dimethoxy-6-(prop-1-en-2-yl)-2,7,20-trioxapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),9,14,16,18-hexaen-12-one
IUPAC Traditional name
cube root

DATABASE IDS

Beilstein Number 6773081
EC Number 201-501-9
MDL Number MFCD09025614
CAS Number 83-79-4
PubChem SID 24278683

PROPERTIES

Purity ≥95%
Boiling Point 210-220 °C/0.5 mmHg(lit.)
Melting Point 159-164 °C(lit.)
GHS Pictograms GHS06
GHS Pictograms GHS09
GHS Signal Word Danger
GHS Hazard statements H301-H315-H319-H335-H410
European Hazard Symbols Toxic Toxic (T)
European Hazard Symbols Nature polluting Nature polluting (N)
GHS Precautionary statements P261-P273-P301 + P310-P305 + P351 + P338-P501
RID/ADR UN 2811 6.1/PG 3
Risk Statements 25-36/37/38-50/53
Safety Statements 22-24/25-36-45-60-61
Hazard Class 6.1
UN Number 2811
Packing Group 3
German water hazard class 3

DETAILS

Description (简体中文)
包装
1, 5, 10, 25 g in glass bottle
Biochem/physiol Actions
Inhibitor of mitochondrial electron transport at NADH:ubiquinone oxidoreductase. It is readily absorbed through the exoskeletons of arthropods, but poorly absorbed cutaneously or from the gastrointestinal tract of mammals. Rotenone is used to induce a Parkinson-like syndrome as an experimental model in rats.
Inhibitor of mitochondrial electron transport. Neurotoxic agent that can produce a Parkinson-like condition as an animal model for study of etiology and interventions.

REFERENCES