Chlorhexidine digluconate solution

• Catalog No.: C9394
• CAS Number: 18472-51-0
• M. F.: C34H54Cl2N10O14
• M. W.: 897.75716

SYNONYMS

• Title: 氯己定 二葡糖酸盐 溶液
• IUPAC name: bis((2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoic acid); N-(4-chlorophenyl)-1-3-(6-{N-[3-(4-chlorophenyl)carbamimidamidomethanimidoyl]amino}hexyl)carbamimidamidomethanimidamide
• IUPAC Traditional name: chlorhexidine digluconate
• Synonyms: 1,6-Bis(N5-[p-chlorophenyl]-N1-biguanido)hexane; 1,1′-Hexamethylenebis(5-[p-chlorophenyl]biguanide)

DATABASE IDS

• MDL Number: MFCD00083599
• CAS Number: 18472-51-0

PROPERTIES

• Concentration: 20% in H2O
• Density: 1.06 g/mL at 25 °C(lit.)
• GHS Signal Word: Warning
• GHS Hazard statements: H400-H411
• European Hazard Symbols: Nature polluting (N)
• Personal Protective Equipment: Eyeshields, Faceshields, Gloves, half-mask respirator (US), multi-purpose combination respirator cartridge (US)
• GHS Precautionary statements: P273
• Risk Statements: 50/53
• Safety Statements: 61
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (English)

Application
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Chlorhexidine is used primarily as a topical antiseptic/disinfectant in wound healing, at catheterization sites, in various dental applications and in surgical scrubs. It has been used to study how essential oils improve skin antisepsis when combined with chlorhexidine digluconate1 and is used for skin permeation studies2 . Chronic rinsing with chlorhexidine has been shown to decrease the saltiness of NaCl and the bitterness of quinine3.
Biochem/physiol Actions
Cationic broad-spectrum antimicrobial agent belonging to the bis(biguanide) family. Its mechanism of action involves destabilization of the outer bacterial membrane. It is used primarily as a topical antiseptic/disinfectant in wound healing, at catheterization sites, in various dental applications and in surgical scrubs.