D-Sphingosine

• Catalog No.: S6879
• CAS Number: 123-78-4
• M. F.: C18H37NO2
• M. W.: 299.49188
• Purity: ~99% (TLC)

SYNONYMS

• IUPAC name: (2S,3R,4E)-2-aminooctadec-4-ene-1,3-diol
• IUPAC Traditional name: sphingosine
• Synonyms: (2S,3R,4E)-2-Amino-4-octadecene-1,3-diol; trans-D-erythro-2-Amino-4-octadecene-1,3-diol; 4-Sphingenine

DATABASE IDS

• Beilstein Number: 1727294
• MDL Number: MFCD00036751
• CAS Number: 123-78-4
• EC Number: 204-651-3

PROPERTIES

• Biological Source: from bovine brain
• Purity: ~99% (TLC)
• Gene Information: human ... PRKCA(5578), PRKCB(5579), PRKCD(5580), PRKCE(5581), PRKCG(5582), PRKCH(5583), PRKCI(5584)
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• Storage Temperature: -20°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
A constituent of cell membranes. Precursor of ceramide. Selective inhibitor of protein kinase C, but does not inhibit protein kinase A or myosin light chain kinase. Inhibitor of calmodulin-dependent enzymes.
Preparation Note
Prepared from sphingomyelin.
Quality
May contain small amounts of structural analogues.