D-Pantethine

• Catalog No.: P3407
• CAS Number: 16816-67-4
• M. F.: C22H42N4O8S2
• M. W.: 554.72088

SYNONYMS

• Title: D-泛硫乙胺
• IUPAC name: (2R)-N-[2-({2-[(2-{3-[(2R)-2,4-dihydroxy-3,3-dimethylbutanamido]propanamido}ethyl)disulfanyl]ethyl}carbamoyl)ethyl]-2,4-dihydroxy-3,3-dimethylbutanamide
• IUPAC Traditional name: pantethine
• Synonyms: 泛硫乙胺; 双泛酰硫乙胺; LBF 因子

DATABASE IDS

• CAS Number: 16816-67-4
• EC Number: 240-842-8
• MDL Number: MFCD00151211

PROPERTIES

• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• Storage Temperature: 2-8°C
• German water hazard class: 2

DETAILS

Description (English)

General description
Cell culture media are generally supplemented with D-Pantothenic acid (vitamin B5) an essential vitamin required for the synthesis of coenzyme-A (CoA) and the metabolism of proteins, carbohydrates, and fats. Cell culture media also contains the inter-convertible sulfur amino acids cysteine and cystine. Pantethine is a dimeric form of pantothenic acid linked by cysteamine bridging groups. The metabolic break-down of pantothine leads to the generation of pantetheine, an intermediate in Co-A biosynthesis. Pantetheine is further metabolized to two pantothenic acid and two cysteamine molecules. Cysteamine is likely to form mixed disulfide with cysteine in solution. The reported activities of pantothenic acid include its hypolipidemic and hypotriglyceridemic effects. The risks/benefits of using D-Pantehine as a cell culture supplement have not been explored.