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N-Acetyl-[D-Trp16]-Endothelin 1 fragment 16-21_Molecular_structure_CAS_143037-33-6)
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N-Acetyl-[D-Trp16]-Endothelin 1 fragment 16-21

Catalog No. E7394 Name Sigma Aldrich
CAS Number 143037-33-6 Website http://www.sigmaaldrich.com
M. F. C46H62N8O10 Telephone 1-800-521-8956
M. W. 887.03208 Fax
Purity Email
Storage Chembase ID: 132132

SYNONYMS

IUPAC name
(3S)-3-{[(1S,2S)-1-{[(1S,2S)-1-{[(1S)-1-carboxy-2-(1H-indol-3-yl)ethyl]carbamoyl}-2-methylbutyl]carbamoyl}-2-methylbutyl]carbamoyl}-3-[(2S)-2-[(2R)-2-acetamido-3-(1H-indol-3-yl)propanamido]-4-methylpentanamido]propanoic acid
IUPAC Traditional name
(3S)-3-{[(1S,2S)-1-{[(1S,2S)-1-{[(1S)-1-carboxy-2-(1H-indol-3-yl)ethyl]carbamoyl}-2-methylbutyl]carbamoyl}-2-methylbutyl]carbamoyl}-3-[(2S)-2-[(2R)-2-acetamido-3-(1H-indol-3-yl)propanamido]-4-methylpentanamido]propanoic acid

DATABASE IDS

PubChem SID 24894644
CAS Number 143037-33-6
MDL Number MFCD00236979

PROPERTIES

Compostion Dye content, ≥95% HPLC
Gene Information human ... EDN1(1906)rat ... Ednra(24326), Ednrb(50672), Gnrhr(81668)
Storage Temperature -20°C
German water hazard class 3

DETAILS

Description (English)
Amino Acid Sequence
Ac-D-Trp-Leu-Asp-Ile-Ile-Trp
Biochem/physiol Actions
ETA antagonist; inhibits ET-1 stimulated arachidonic acid release in rabbit vascular smooth muscle cells.

REFERENCES