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Inosine

Catalog No. I1024 Name Sigma Aldrich
CAS Number 58-63-9 Website http://www.sigmaaldrich.com
M. F. C10H12N4O5 Telephone 1-800-521-8956
M. W. 268.22608 Fax
Purity ≥99% Email
Storage Chembase ID: 119255

SYNONYMS

IUPAC name
9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-6,9-dihydro-1H-purin-6-one
IUPAC Traditional name
9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one
Synonyms
Hypoxanthine 9-β-D-ribofuranoside
(-)-Inosine

DATABASE IDS

Beilstein Number 624896
EC Number 200-390-4
MDL Number MFCD00066770
CAS Number 58-63-9

PROPERTIES

Antion Traces chloride (Cl-): ≤0.05%
Antion Traces sulfate (SO42-): ≤0.05%
Cation Traces Al: ≤0.0005%
Cation Traces Ca: ≤0.0005%
Cation Traces Cu: ≤0.0005%
Cation Traces Fe: ≤0.0005%
Cation Traces K: ≤0.005%
Cation Traces Mg: ≤0.0005%
Cation Traces NH4+: ≤0.05%
Cation Traces Na: ≤0.005%
Cation Traces Pb: ≤0.001%
Cation Traces Zn: ≤0.0005%
Ignition Residue ≤0.1%
Impurities ≤0.0005% Phosphorus (P)
Impurities ≤0.2% Insoluble matter
Purity ≥99%
Melting Point 222-226 °C (dec.)(lit.)
Solubility H2O: soluble0.5 M, clear, colorless
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
German water hazard class 2

DETAILS

Description (English)
Biochem/physiol Actions
Inosine is a potent stimulator of nerve growth factor (NGF) induced neurite outgrowth. The elevated levels of inosine in brain following injury are associated with the increased expression proteins related to axonal regeneration and growth. Mice given inosine demonstrated enhanced recovery of fine motor control following ischemic brain damage. Inosine may be used in studies of the process A-to-I RNA editing.

REFERENCES