3-Maleimidobenzoic acid N-hydroxysuccinimide ester

• Catalog No.: M8759
• CAS Number: 58626-38-3
• M. F.: C15H10N2O6
• M. W.: 314.2497

SYNONYMS

• Title: 3-马来酰亚胺基苯甲酸琥珀酰亚胺酯
• IUPAC name: 2,5-dioxopyrrolidin-1-yl 3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)benzoate
• IUPAC Traditional name: 2,5-dioxopyrrolidin-1-yl 3-(2,5-dioxopyrrol-1-yl)benzoate
• Synonyms: MBS

DATABASE IDS

• CAS Number: 58626-38-3
• Beilstein Number: 1505254
• PubChem SID: 24897286
• MDL Number: MFCD00005514
• EC Number: 261-368-8

PROPERTIES

• Solubility: ethyl acetate or DMF: ≤20 mg/mL (may require addition of solvent to coupling buffer to at least 5% to maintain solubility)
• GHS Signal Word: Warning
• GHS Hazard statements: H315-H319-H335
• European Hazard Symbols: Irritant (Xi)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• GHS Precautionary statements: P261-P305 + P351 + P338
• Risk Statements: 36/37/38
• Safety Statements: 26-36
• Storage Temperature: -20°C
• German water hazard class: 3

DETAILS

Description (简体中文)

Application
对伯胺和巯基具有反应性的双异官能化交联剂。通常，初始反应在 pH 为 7.0 时，通过酰胺键偶联至含伯胺的分子，然后在相同 pH 通过硫醚偶联至含巯基的化合物。用于制备酶免疫交联剂和半抗原载体分子偶联物。
Other Notes
芳基马来酰亚胺比烷基马来酰亚胺连接基更不稳定。