Tamoxifen citrate salt

• Catalog No.: T9262
• CAS Number: 54965-24-1
• M. F.: C32H37NO8
• M. W.: 563.63808
• Purity: ≥99%

SYNONYMS

• Title: 他莫昔芬 柠檬酸盐
• IUPAC name: (2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}ethyl)dimethylamine; 2-hydroxypropane-1,2,3-tricarboxylic acid
• IUPAC Traditional name: citro; tamoxifen
• Synonyms: (Z)-1-(对二甲基氨基乙氧基苯基)-1,2-二苯基-1-丁烯

DATABASE IDS

• PubChem SID: 24278059
• MDL Number: MFCD00058321
• EC Number: 259-415-2
• CAS Number: 54965-24-1

PROPERTIES

• Purity: ≥99%
• Gene Information: human ... PRKCA(5578), PRKCB(5579), PRKCD(5580), PRKCE(5581), PRKCG(5582), PRKCH(5583), PRKCI(5584)
• GHS Signal Word: Danger
• GHS Hazard statements: H302-H350-H360
• European Hazard Symbols: Toxic (T)
• Personal Protective Equipment: Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
• GHS Precautionary statements: P201-P308 + P313
• Risk Statements: 45-60-61-22-64
• RTECS: KH2387000
• Safety Statements: 36/37/39-45
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Protein kinase C inhibitor. Induces apoptosis in human malignant glioma cell lines. Tamoxifen and its metabolite 4-hydroxytamoxifen are selective estrogen response modifiers (SERMs) that act as estrogen antagonists in mammary gland. Blocks estradiol-stimulated VEGF production in breast tumor cells.