Bupropion hydrochloride

• Catalog No.: B102
• CAS Number: 31677-93-7
• M. F.: C13H19Cl2NO
• M. W.: 276.20206
• Purity: ≥98% (HPLC)

SYNONYMS

• IUPAC name: 2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one hydrochloride
• IUPAC Traditional name: bupropion hydrochloride
• Synonyms: (±)-1-(3-Chlorophenyl)-2-[(1,1-dimethylethyl)amino]-1-propanone hydrochloride

DATABASE IDS

• CAS Number: 31677-93-7
• EC Number: 250-759-9
• MDL Number: MFCD00055209
• PubChem SID: 24277884

PROPERTIES

• Purity: ≥98% (HPLC)
• Gene Information: human ... DRD1(1812), DRD2(1813), DRD3(1814), DRD4(1815), DRD5(1816)
• Apperance: white solid
• Solubility: ethanol: soluble193 mg/mL (solutions may be stored for several days at 4 °C.)
• Solubility: H2O: soluble312 mg/mL (solutions may be stored for several days at 4 °C.)
• Solubility: 1 M HCl: soluble333 mg/mL (solutions may be stored for several days at 4 °C.)
• GHS Signal Word: Warning
• GHS Hazard statements: H302
• European Hazard Symbols: Harmful (Xn)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Faceshields, Gloves
• Risk Statements: 22
• RTECS: UG8858000
• Safety Statements: 36
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Inhibits the dopamine and norepinephrine transporters with Kis of 2.8 μM and 1.4 μM, respectively. Does not inhibit the serotonin transporter (Ki = 45 μM). Antidepressant.