Nystatin Suspension

• Catalog No.: N1638
• CAS Number: 1400-61-9
• M. F.: C47H75NO17
• M. W.: 926.0949

SYNONYMS

• IUPAC name: (1S,3R,4R,7R,9R,11R,15S,16S,17R,18S,19Z,21Z,25Z,27Z,29Z,31Z,33R,35S,36R,37S)-33-{[(2R,3S,4S,5S,6R)-4-amino-3,5-dihydroxy-6-methyloxan-2-yl]oxy}-1,3,4,7,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,25,27,29,31-hexaene-36-carboxylic acid
• IUPAC Traditional name: (1S,3R,4R,7R,9R,11R,15S,16S,17R,18S,19Z,21Z,25Z,27Z,29Z,31Z,33R,35S,36R,37S)-33-{[(2R,3S,4S,5S,6R)-4-amino-3,5-dihydroxy-6-methyloxan-2-yl]oxy}-1,3,4,7,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,25,27,29,31-hexaene-36-carboxylic acid

DATABASE IDS

• CAS Number: 1400-61-9
• PubChem SID: 24897511

PROPERTIES

• Concentration: 10,000 unit/mL in DPBS
• Impurities: endotoxin, tested
• Shipped in: dry ice
• Sterility: aseptically processed
• Suitability: suitable for cell culture
• Apperance: yellow suspension
• Storage Temperature: -20°C
• German water hazard class: 2

DETAILS

Description (English)

Application
Recommended for use in cell culture applications at 24 ml/L. Used as a fungal membrane (ergosterol binding) pore forming agent and to create nystatin/ergosterol based ion channels in lipid bilayers and as a lipid raft-inhibiting reagent and membrane associated cholesterol aggregator.
Biochem/physiol Actions
Mode of Action: Increases the permeability of the cell membrane of sensitive fungi by binding to sterols.Antimicrobial spectrum: Yeasts and molds.
Caution
Stable at 37 °C for 3 days.
Protocols & Applications
Antibiotic Selector for application, solubility, solution stability, working concentration, and mode of action information