(+)-Pentazocine

• Catalog No.: P127
• CAS Number: 7361-76-4
• M. F.: C19H27NO
• M. W.: 285.42378

SYNONYMS

• IUPAC name: (1S,9S,13S)-1,13-dimethyl-10-(3-methylbut-2-en-1-yl)-10-azatricyclo[7.3.1.0^2,^7]trideca-2,4,6-trien-4-ol
• IUPAC Traditional name: (1S,9S,13S)-1,13-dimethyl-10-(3-methylbut-2-en-1-yl)-10-azatricyclo[7.3.1.0^2,^7]trideca-2,4,6-trien-4-ol

DATABASE IDS

• PubChem SID: 24898179
• CAS Number: 7361-76-4

PROPERTIES

• Gene Information: human ... EBP(10682)rat ... Chrm1(25229), Chrm2(81645), Drd2(24318), Oprm1(25601)
• Apperance: white solid
• Optical Rotation: [α]23/D +134.6°, c = 1 in chloroform(lit.)
• Drug Control: USDEA Schedule IV; Home Office Schedule 3; stupéfiant; kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada
• GHS Signal Word: Warning
• GHS Hazard statements: H302-H312-H332
• European Hazard Symbols: Harmful (Xn)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• GHS Precautionary statements: P280
• Risk Statements: 20/21/22
• Safety Statements: 36
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
σ receptor agonist; active enantiomer of pentazocine.
Caution
Photosensitive
Reconstitution
A 10 mM solution of (+)-pentazocine is prepared by warming 28.5 mg of (+)-pentazocine free base in 2 mL of 0.1N HCl with shaking or sonication. When all solids have dissolved, the solution is cooled to room temperature and diluted with 10 mL of pH 7 buffer. Solutions should be freshly prepared, since cooling below room temperature may result in precipitation.