Cocaine free base

• Catalog No.: C8912
• CAS Number: 50-36-2
• M. F.: C17H21NO4
• M. W.: 303.35294

SYNONYMS

• Title: 可卡因 游离碱
• IUPAC name: methyl (1R,2R,3S,5S)-3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate
• IUPAC Traditional name: cocaine
• Synonyms: 苯甲酰甲基芽子碱

DATABASE IDS

• EC Number: 200-032-7
• MDL Number: MFCD00056906
• CAS Number: 50-36-2
• PubChem SID: 24893116

PROPERTIES

• Gene Information: human ... DRD3(1814), KCNH1(3756), KCNH2(3757), SCN10A(6336), SCN11A(11280), SCN5A(6331), SLC6A2(6530), SLC6A3(6531), SLC6A4(6532)mouse ... Slc6a2(20538)rat ... Chrm1(25229), Slc6a3(24898), Slc6a4(25553)
• Drug Control: USDEA Schedule II; Home Office Schedule 2; stupéfiant; kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada
• GHS Signal Word: Danger
• GHS Hazard statements: H301-H311-H317-H331
• European Hazard Symbols: Toxic (T)
• Personal Protective Equipment: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
• GHS Precautionary statements: P261-P280-P301 + P310-P311
• RID/ADR: UN 1544 6.1/PG 2
• Risk Statements: 23/24/25-43
• RTECS: YM2800000
• Safety Statements: 22-36/37/39-45
• Hazard Class: 6.1
• UN Number: 1544
• Packing Group: 2
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Inhibits the dopamine, norepinephrine, and serotonin transporters with Kis of about 300 nM, 900 nM, and 400 nM, respectively. Unlike amphetamines, it has no effect on catecholamine release.