Home > Compound List > Product Information
1,1-Dimethylbiguanide hydrochloride_Molecular_structure_CAS_1115-70-4)
Click picture or here to close

1,1-Dimethylbiguanide hydrochloride

Catalog No. D5035 Name Sigma Aldrich
CAS Number 1115-70-4 Website http://www.sigmaaldrich.com
M. F. C4H12ClN5 Telephone 1-800-521-8956
M. W. 165.62458 Fax
Purity ≥97% Email
Storage Chembase ID: 72826

SYNONYMS

Title
甲福明 盐酸盐
IUPAC name
1-carbamimidamido-N,N-dimethylmethanimidamide hydrochloride
IUPAC Traditional name
metformin hydrochloride
Synonyms
二甲双胍

DATABASE IDS

MDL Number MFCD00012582
EC Number 214-230-6
PubChem SID 24893918
CAS Number 1115-70-4

PROPERTIES

Purity ≥97%
Melting Point 223-226 °C(lit.)
European Hazard Symbols Harmful Harmful (Xn)
Risk Statements 22-36/38
RTECS DU1800000
Safety Statements 26-36
German water hazard class 3

DETAILS

Description (简体中文)
Biochem/physiol Actions
甲福明是一种抗糖尿病药,可降低血糖水平,提高胰岛素灵敏度。其代谢作用(包括抑制肝脏糖异生作用)至少部分是通过激活 LKB1-AMPK(AMP-活化蛋白激酶)通路进行介导。该通路的激活也涉及到癌细胞系中甲福明的抗增殖和促凋亡作用。

REFERENCES