Amrinone

• Catalog No.: A4056
• CAS Number: 60719-84-8
• M. F.: C10H9N3O
• M. W.: 187.19796

SYNONYMS

• IUPAC name: 3-amino-5-(pyridin-4-yl)-1,2-dihydropyridin-2-one
• IUPAC Traditional name: amrinone
• Synonyms: Inamrinone; 5-Amino-(3,4′-bipyridin)-6(1H)-one

DATABASE IDS

• EC Number: 262-390-0
• MDL Number: MFCD00083228
• CAS Number: 60719-84-8
• PubChem SID: 24890741

PROPERTIES

• Gene Information: rat ... Pde3a(50678)
• GHS Signal Word: Danger
• GHS Hazard statements: H301
• European Hazard Symbols: Toxic (T)
• Personal Protective Equipment: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
• GHS Precautionary statements: P301 + P310
• RID/ADR: UN 2811 6.1/PG 3
• Risk Statements: 25
• RTECS: DW2500000
• Safety Statements: 28-45
• Storage Temperature: 2-8°C
• Hazard Class: 6.1
• UN Number: 2811
• Packing Group: 3
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Simple, non-glycoside cardiotonic agent, possibly via its phosphodiesterase III (PDE-III) inhibitory action.1
Simple, non-glycoside cardiotonic agent, possibly via its phosphodiesterase III (PDE-III) inhibitory action.1 Independent of its cardiac effects, amrinone provides protection against ischemia-reperfusion injury in kidney,2 liver,3 and heart.4