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S-(-)-Carbidopa_Molecular_structure_CAS_28860-95-9)
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S-(-)-Carbidopa

Catalog No. C126 Name Sigma Aldrich
CAS Number 28860-95-9 Website http://www.sigmaaldrich.com
M. F. C10H14N2O4 Telephone 1-800-521-8956
M. W. 226.22916 Fax
Purity Email
Storage Chembase ID: 103979

SYNONYMS

IUPAC name
3-(3,4-dihydroxyphenyl)-2-hydrazinyl-2-methylpropanoic acid
IUPAC Traditional name
carbidopa
Synonyms
S-(-)-α-Hydrazino-3,4-dihydroxy-2-methylbenzenepropanoic acid
(S)-3-(3,4-Dihydroxyphenyl)-2-hydrazino-2-methylpropanoic acid

DATABASE IDS

CAS Number 28860-95-9
PubChem SID 24277889
MDL Number MFCD00069231
EC Number 249-271-9

PROPERTIES

Gene Information human ... DDC(1644)
Absorption Wavelength εmax/282.5 nm, methanol 2950
Apperance white solid
Optical Rotation [α]26/D -13.82°, c = 0.3 in methanol(lit.)
RTECS MW5298000
Storage Temperature -20°C
German water hazard class 3

DETAILS

Description (English)
Caution
Light sensitive
Biochem/physiol Actions
Peripheral inhibitor of L-aromatic amino acid decarboxylase. When co-administered with L-DOPA, it prevents extra-CNS conversion to dopamine, thereby increasing CNS concentrations of effective compounds. Selectively cytotoxic to human pulmonary carcinoid and small cell lung carcinoma cells by increasing H2O2 in these cell lines, which are sensitive to reactive oxygen species.1

REFERENCES