(±)-Methadone hydrochloride

• Catalog No.: M0267
• CAS Number: 1095-90-5
• M. F.: C21H28ClNO
• M. W.: 345.90612
• Purity: ≥98% (TLC)

SYNONYMS

• IUPAC name: 6-(dimethylamino)-4,4-diphenylheptan-3-one hydrochloride
• IUPAC Traditional name: methadone hydrochloride
• Synonyms: 6-Dimethylamino-4,4-diphenylheptan-3-one hydrochloride

DATABASE IDS

• MDL Number: MFCD00058014
• EC Number: 214-140-7
• CAS Number: 1095-90-5
• PubChem SID: 24896546

PROPERTIES

• Purity: ≥98% (TLC)
• Apperance: white to off-white powder
• Solubility: H2O: >50 mg/mL, clear, colorless to yellow
• Drug Control: USDEA Schedule II; Home Office Schedule 2; stupéfiant; kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada
• GHS Signal Word: Danger
• GHS Hazard statements: H300
• European Hazard Symbols: Toxic (T)
• Personal Protective Equipment: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
• GHS Precautionary statements: P264-P301 + P310
• RID/ADR: UN 2811 6.1/PG 2
• Risk Statements: 25
• RTECS: MJ6300000
• Safety Statements: 45
• Hazard Class: 6.1
• UN Number: 2811
• Packing Group: 2
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
μ opioid receptor agonist that desensitizes both the μ opioid receptor and the δ opioid receptor on chronic exposure; narcotic analgesic, characterized by a gradual onset of action and prolonged, milder withdrawal; may also block L-type calcium channels independently of its effects on opioid receptors.