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[D-Arg1, D-Trp7,9, Leu11]-Substance P_Molecular_structure_CAS_91224-37-2)
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[D-Arg1, D-Trp7,9, Leu11]-Substance P

Catalog No. S3641 Name Sigma Aldrich
CAS Number 91224-37-2 Website http://www.sigmaaldrich.com
M. F. C75H108N20O13 Telephone 1-800-521-8956
M. W. 1497.78622 Fax
Purity ≥97% (HPLC) Email
Storage Chembase ID: 131218

SYNONYMS

IUPAC name
(2S)-2-{[(2S)-1-[(2S)-6-amino-2-{[(2S)-1-[(2R)-2-amino-5-carbamimidamidopentanoyl]pyrrolidin-2-yl]formamido}hexanoyl]pyrrolidin-2-yl]formamido}-N-[(1S)-3-carbamoyl-1-{[(1R)-1-{[(1S)-1-{[(1R)-1-{[(1S)-1-{[(1S)-1-carbamoyl-3-methylbutyl]carbamoyl}-3-methylbutyl]carbamoyl}-2-(1H-indol-3-yl)ethyl]carbamoyl}-2-phenylethyl]carbamoyl}-2-(1H-indol-3-yl)ethyl]carbamoyl}propyl]pentanediamide
IUPAC Traditional name
(2S)-2-{[(2S)-1-[(2S)-6-amino-2-{[(2S)-1-[(2R)-2-amino-5-carbamimidamidopentanoyl]pyrrolidin-2-yl]formamido}hexanoyl]pyrrolidin-2-yl]formamido}-N-[(1S)-3-carbamoyl-1-{[(1R)-1-{[(1S)-1-{[(1R)-1-{[(1S)-1-{[(1S)-1-carbamoyl-3-methylbutyl]carbamoyl}-3-methylbutyl]carbamoyl}-2-(1H-indol-3-yl)ethyl]carbamoyl}-2-phenylethyl]carbamoyl}-2-(1H-indol-3-yl)ethyl]carbamoyl}propyl]pentanediamide
Synonyms
Spantide I

DATABASE IDS

CAS Number 91224-37-2
MDL Number MFCD00076805

PROPERTIES

Purity ≥97% (HPLC)
Gene Information human ... TAC1(6863), TACR1(6869)mouse ... TAC1(21333), TACR1(21336)rat ... TAC1(24806), TACR1(24807)
Storage Temperature -20°C
German water hazard class 3

DETAILS

Description (English)
Amino Acid Sequence
D-Arg-Pro-Lys-Pro-Gln-Gln-D-Trp-Phe-D-Trp-Leu-Leu-NH2
Biochem/physiol Actions
Potent substance P antagonist with weak histamine-releasing action

REFERENCES