Ibogaine hydrochloride

• Catalog No.: I7003
• CAS Number: 5934-55-4
• M. F.: C20H27ClN2O
• M. W.: 346.89418

SYNONYMS

• IUPAC name: 17-ethyl-7-methoxy-3,13-diazapentacyclo[13.3.1.0^2,^1^0.0^4,^9.0^1^3,^1^8]nonadeca-2(10),4(9),5,7-tetraene hydrochloride
• IUPAC Traditional name: 17-ethyl-7-methoxy-3,13-diazapentacyclo[13.3.1.0^2,^1^0.0^4,^9.0^1^3,^1^8]nonadeca-2(10),4(9),5,7-tetraene hydrochloride

DATABASE IDS

• CAS Number: 5934-55-4
• MDL Number: MFCD00167426
• EC Number: 227-687-1

PROPERTIES

• Solubility: H2O: soluble
• Solubility: methanol: soluble
• GHS Signal Word: Warning
• GHS Hazard statements: H302
• European Hazard Symbols: Harmful (Xn)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Faceshields, Gloves
• Risk Statements: 22
• RTECS: NH6730000
• Safety Statements: 22-26-37/39-45
• German water hazard class: 3

DETAILS

Description (English)

Preparation Note
Alkaloid isolated from the African shrub, Tabernanthe iboga.
Biochem/physiol Actions
Ibogaine is a central nervous system stimulant and hallucinogen that has been reported to be a σ2 agonist, a noncompetitive NMDA receptor antagonist at the phencyclidine site and an enhancer of purinergic muscle contractions. It is also a competitive inhibitor of serotonin and dopamine transport. It is an anti-convulsant and has anti-addictive properties against cocaine and heroin.