Diazepam

• Catalog No.: D0899
• CAS Number: 439-14-5
• M. F.: C16H13ClN2O
• M. W.: 284.74022

SYNONYMS

• Title: 地西泮
• IUPAC name: 7-chloro-1-methyl-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-2-one
• IUPAC Traditional name: diazepam
• Synonyms: 7-Chloro-1-methyl-5-phenyl-3H-1,4-benzodiazepin-2(1H)-one; Ro 5-2807

DATABASE IDS

• PubChem SID: 24893306
• CAS Number: 439-14-5
• EC Number: 207-122-5
• MDL Number: MFCD00057323

PROPERTIES

• Gene Information: human ... GABRA1(2554), GABRA2(2555), GABRA3(2556), GABRA5(2558), GABRA6(2559)rat ... Gabra1(29705), Gabra2(29706)
• Solubility: 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: soluble1.6 mg/mL
• Solubility: DMF: soluble
• Solubility: H2O: slightly soluble
• Solubility: ethanol: soluble
• Drug Control: USDEA Schedule IV; Home Office Schedule 4.1; psychotrope; kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada
• GHS Signal Word: Danger
• GHS Hazard statements: H301 + H311
• European Hazard Symbols: Harmful (Xn)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Faceshields, Gloves
• GHS Precautionary statements: P280-P301 + P310-P312
• RID/ADR: UN 2811 6.1/PG 3
• Risk Statements: 21/22
• RTECS: DF1575000
• Safety Statements: 36/37
• Hazard Class: 6.1
• UN Number: 2811
• Packing Group: 3
• German water hazard class: 2

DETAILS

Description (English)

Biochem/physiol Actions
Benzodiazepine anxiolytic; prototype ligand for the GABAA receptor benzodiazepine modulatory site.