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Timolol maleate salt_Molecular_structure_CAS_26921-17-5)
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Timolol maleate salt

Catalog No. T6394 Name Sigma Aldrich
CAS Number 26921-17-5 Website http://www.sigmaaldrich.com
M. F. C17H28N4O7S Telephone 1-800-521-8956
M. W. 432.49182 Fax
Purity ≥98% (TLC) Email
Storage Chembase ID: 131071

SYNONYMS

IUPAC name
(2Z)-but-2-enedioic acid; tert-butyl[(2S)-2-hydroxy-3-{[4-(morpholin-4-yl)-1,2,5-thiadiazol-3-yl]oxy}propyl]amine
IUPAC Traditional name
maleic acid; timolol
Synonyms
S-(-)-1-(t-Butylamino)-3-[(4-morpholino-1,2,5-thiadiazol-3-yl)oxy]-2-propanol maleate salt

DATABASE IDS

CAS Number 26921-17-5
MDL Number MFCD00058356
PubChem SID 24277810
EC Number 248-111-5

PROPERTIES

Purity ≥98% (TLC)
Gene Information human ... ADRB1(153), ADRB2(154), ADRB3(155)
Absorption Wavelength ε1M/294 nm 8,700
Apperance white to off-white powder
Melting Point 202-203 °C(lit.)
Optical Rotation [α]25/D -5.4°, c = 4.9 in 1 M HCl(lit.)
Solubility H2O: soluble
Solubility ethanol: soluble
GHS Pictograms GHS07
GHS Pictograms GHS08
GHS Signal Word Warning
GHS Hazard statements H302-H361
European Hazard Symbols Harmful Harmful (Xn)
Personal Protective Equipment Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
GHS Precautionary statements P281
Risk Statements 63-22
RTECS UA8475000
Safety Statements 36
German water hazard class 3

DETAILS

Description (English)
Biochem/physiol Actions
Non-selective β-adrenoceptor antagonist; vasodilator; class II anti-arrhythmic; anti-glaucoma agent

REFERENCES