Mazindol

• Catalog No.: M2017
• CAS Number: 22232-71-9
• M. F.: C16H13ClN2O
• M. W.: 284.74022
• Purity: ≥98% (TLC)

SYNONYMS

• IUPAC name: 5-(4-chlorophenyl)-2H,3H,5H-imidazo[2,1-a]isoindol-5-ol
• IUPAC Traditional name: mazindol
• Synonyms: 5-(4-Chlorophenyl)-2,5-dihydro-3H-imidazo[2,1-a]isoindol-5-ol

DATABASE IDS

• MDL Number: MFCD00864480
• PubChem SID: 24896596
• EC Number: 244-857-0
• CAS Number: 22232-71-9

PROPERTIES

• Purity: ≥98% (TLC)
• Gene Information: human ... SLC6A2(6530), SLC6A3(6531), SLC6A4(6532)rat ... Htr1a(24473), Htr2a(29595), Slc6a3(24898), Slc6a4(25553)
• Apperance: white powder
• Solubility: DMSO: soluble10 mg/mL
• Drug Control: USDEA Schedule IV; Home Office Schedule 3; psychotrope; kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada
• GHS Signal Word: Danger
• GHS Hazard statements: H300-H311-H331
• European Hazard Symbols: Toxic (T)
• Personal Protective Equipment: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
• GHS Precautionary statements: P261-P264-P280-P301 + P310-P311
• RID/ADR: UN 2811 6.1/PG 2
• Risk Statements: 23/24/25
• RTECS: NI2975000
• Safety Statements: 36/37/39-45
• Hazard Class: 6.1
• UN Number: 2811
• Packing Group: 2
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Anorectic agent; inhibits the dopamine, norepinephrine and serotonin transporters with Kis of 27.6 nM, 3.2 nM, and 153 nM, respectively.