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Erythromycin

Catalog No. E6376 Name Sigma Aldrich
CAS Number 114-07-8 Website http://www.sigmaaldrich.com
M. F. C37H67NO13 Telephone 1-800-521-8956
M. W. 733.92678 Fax
Purity Email
Storage Chembase ID: 84

SYNONYMS

Title
红霉素
IUPAC name
(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy}-3,5,7,9,11,13-hexamethyl-1-oxacyclotetradecane-2,10-dione
IUPAC Traditional name
erythromycin

DATABASE IDS

CAS Number 114-07-8
EC Number 204-040-1
MDL Number MFCD00084654
Beilstein Number 75279
PubChem SID 24894626

PROPERTIES

Potency ≥850 μg per mg
Gene Information human ... ABCB1(5243), CYP3A4(1576), MLNR(2862)mouse ... Abcb1a(18671), Abcb1b(18669)
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
RTECS KF437500
German water hazard class 3

DETAILS

Description (English)
Biochem/physiol Actions
Mode of Action: Inhibits elongation at transpeptidation step.Antimicrobial spectrum: Gram-negative and Gram-positive bacteria.
Mode of Action: Inhibits protein synthesis (elongation) at the level of transpeptidation (aminoacyl translocation A-site to P-site).Antimicrobial spectrum: Gram-negative and Gram-positive bacteria.
Other Notes
Macrolide antibiotic.

REFERENCES