Novobiocin sodium

• Catalog No.: N6160
• CAS Number: 1476-53-5
• M. F.: C31H35N2NaO11
• M. W.: 634.60617

SYNONYMS

• Title: 新生霉素 钠
• IUPAC name: sodium 7-{[(2R,3R,4S,5R)-4-(carbamoyloxy)-3-hydroxy-5-methoxy-6,6-dimethyloxan-2-yl]oxy}-3-[4-hydroxy-3-(3-methylbut-2-en-1-yl)benzamido]-8-methyl-2-oxo-2H-chromen-4-olate
• IUPAC Traditional name: sodium 7-{[(2R,3R,4S,5R)-4-(carbamoyloxy)-3-hydroxy-5-methoxy-6,6-dimethyloxan-2-yl]oxy}-3-[4-hydroxy-3-(3-methylbut-2-en-1-yl)benzamido]-8-methyl-2-oxochromen-4-olate
• Synonyms: 新生霉素 钠盐

DATABASE IDS

• EC Number: 216-023-6
• PubChem SID: 24897774
• Beilstein Number: 3892910
• CAS Number: 1476-53-5

PROPERTIES

• Suitability: meets USP testing specifications
• GHS Signal Word: Warning
• GHS Hazard statements: H317-H319
• European Hazard Symbols: Irritant (Xi)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Faceshields, Gloves
• GHS Precautionary statements: P280-P305 + P351 + P338
• Risk Statements: 36-43
• RTECS: RD5425000
• Safety Statements: 26-36/37
• Storage Temperature: 2-8°C
• German water hazard class: 2

DETAILS

Description (English)

Application
For the production of positively supercoiled plasmid DNA.1 Inhibitor of bacterial DNA gyrase and eukaryotic DNA topoisomerase.2 Inhibitor of retrovirus RNA-dependent DNA-polymerase.3
Biochem/physiol Actions
Mode of Action: Inhibits DNA synthesis by inhibiting the enzyme Topoisomerase II.Antimicrobial spectrum: Gram-positive bacterial.