Tetracycline hydrochloride

• Catalog No.: T8032
• CAS Number: 64-75-5
• M. F.: C22H25ClN2O8
• M. W.: 480.8955

SYNONYMS

• Title: 四环素 盐酸盐
• IUPAC name: (4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide hydrochloride
• IUPAC Traditional name: tetracycline hydrochloride

DATABASE IDS

• MDL Number: MFCD00078142
• CAS Number: 64-75-5
• Beilstein Number: 3844873
• PubChem SID: 24900496
• EC Number: 200-593-8

PROPERTIES

• Sterility: γ-irradiated
• Apperance: powder
• Melting Point: 220-223 °C(lit.)
• GHS Signal Word: Warning
• GHS Hazard statements: H315-H319-H335
• European Hazard Symbols: Irritant (Xi)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• GHS Precautionary statements: P261-P305 + P351 + P338
• Risk Statements: 36/37/38
• RTECS: QI9100000
• Safety Statements: 26-36
• Storage Temperature: -20°C
• German water hazard class: 2

DETAILS

Description (简体中文)

Application
建议以 10-20μg/ml 的量用于分子生物学应用。
Biochem/physiol Actions
Mode of Action: Inhibits protein synthesis (elongation) by preventing binding of aminoacyl-tRNA to the 30S subunit. Antimicrobial spectrum: Gram-negative and Gram-positive bacteria.Mode of Resistance: Loss of cell wall permeability.
Reconstitution
直接在样品瓶中用无菌水 (10mg/ml) 制备储存液。储存液在 2-8°C 下保存不应超过一周；四环素在水溶液中会发生水解。