Kanamycin sulfate from Streptomyces kanamyceticus

• Catalog No.: K1637
• CAS Number: 25389-94-0
• M. F.: C18H38N4O15S
• M. W.: 582.57712

SYNONYMS

• Title: 卡那霉素 硫酸酯 来源于卡那霉素链霉菌
• IUPAC name: (2R,3S,4S,5R,6R)-2-(aminomethyl)-6-{[(1R,2R,3S,4R,6S)-4,6-diamino-3-{[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-2-hydroxycyclohexyl]oxy}oxane-3,4,5-triol; sulfuric acid
• IUPAC Traditional name: kanamycin; sulfuric acid
• Synonyms: 卡那霉素碱 硫酸盐; 卡那霉素 A

DATABASE IDS

• MDL Number: MFCD00070253
• EC Number: 246-933-9
• PubChem SID: 24896209
• CAS Number: 25389-94-0

PROPERTIES

• GHS Signal Word: Danger
• GHS Hazard statements: H360
• European Hazard Symbols: Toxic (T)
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• GHS Precautionary statements: P201-P308 + P313
• Risk Statements: 61
• RTECS: NZ3225030
• Safety Statements: 53-45
• German water hazard class: 2
• Potency: ≥750 μg per mg
• Quality Level: PREMIUM
• Suitability: meets USP testing specifications
• Apperance: powder
• Solubility: H2O: soluble10-50 mg/mL (As a stock solution. Stock solutions should be stored at 2-8°C. Stable at 37°C for 5 days.)

DETAILS

Description (English)

Application
Used in biotechnology applications to inhibit protein synthesis. Used as a selection agent for cells transformed with kanamycin B (neoR, kanR) resistance gene.
Biochem/physiol Actions
Mode of Action: Binds to 70S ribosomal subunit; inhibits translocation; elicits miscoding. Antimicrobial spectrum: Gram-negative and Gram-positive bacteria, and mycoplasma.