Vincristine sulfate

• Catalog No.: V8388
• CAS Number: 2068-78-2
• M. F.: C46H58N4O14S
• M. W.: 923.03612

SYNONYMS

• Title: 长春新碱 硫酸酯
• IUPAC name: sulfuric acid methyl (1R,9R,10S,11R,12R,19R)-11-(acetyloxy)-12-ethyl-4-[(13S,15R,17S)-17-ethyl-17-hydroxy-13-(methoxycarbonyl)-1,11-diazatetracyclo[13.3.1.0^4,^1^2.0^5,^1^0]nonadeca-4(12),5,7,9-tetraen-13-yl]-8-formyl-10-hydroxy-5-methoxy-8,16-diazapentacyclo[10.6.1.0^1,^9.0^2,^7.0^1^6,^1^9]nonadeca-2(7),3,5,13-tetraene-10-carboxylate
• IUPAC Traditional name: sulfuric acid methyl (1R,9R,10S,11R,12R,19R)-11-(acetyloxy)-12-ethyl-4-[(13S,15R,17S)-17-ethyl-17-hydroxy-13-(methoxycarbonyl)-1,11-diazatetracyclo[13.3.1.0^4,^1^2.0^5,^1^0]nonadeca-4(12),5,7,9-tetraen-13-yl]-8-formyl-10-hydroxy-5-methoxy-8,16-diazapentacyclo[10.6.1.0^1,^9.0^2,^7.0^1^6,^1^9]nonadeca-2(7),3,5,13-tetraene-10-carboxylate
• Synonyms: 醛基长春碱 硫酸盐; 长春新碱 硫酸盐; 长春醛碱 硫酸盐; VCR

DATABASE IDS

• Beilstein Number: 3924631
• CAS Number: 2068-78-2
• EC Number: 218-190-0
• MDL Number: MFCD00084729
• PubChem SID: 24900771

PROPERTIES

• Suitability: meets USP testing specifications
• GHS Signal Word: Danger
• GHS Hazard statements: H300-H341-H361fd
• European Hazard Symbols: Toxic (T)
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• GHS Precautionary statements: P264-P281-P301 + P310
• RID/ADR: UN 2811 6.1/PG 2
• Risk Statements: 63-25-62-68
• RTECS: OH6340000
• Safety Statements: 36/37-45
• Storage Temperature: -20°C
• Hazard Class: 6.1
• UN Number: 2811
• Packing Group: 2
• German water hazard class: 3

DETAILS

Description (English)

Application
Widely used in cancer research. In studies on multi-drug resistance. Used to inhibit cell cycle progression at M-phase. Used to inhibit monoamine oxidase (MAO).