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N-Ethylmaleimide

Catalog No. E1271 Name Sigma Aldrich
CAS Number 128-53-0 Website http://www.sigmaaldrich.com
M. F. C6H7NO2 Telephone 1-800-521-8956
M. W. 125.12528 Fax
Purity ≥98% (HPLC) Email
Storage Chembase ID: 2676

SYNONYMS

Title
N-乙基马来酰亚胺
IUPAC name
1-ethyl-2,5-dihydro-1H-pyrrole-2,5-dione
IUPAC Traditional name
N-ethylmaleimide
Synonyms
NEM

DATABASE IDS

CAS Number 128-53-0
MDL Number MFCD00005509
PubChem SID 24894398
Beilstein Number 112448
EC Number 204-892-4

PROPERTIES

Personal Protective Equipment Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
GHS Precautionary statements P264-P280-P301 + P310-P305 + P351 + P338-P310
RID/ADR UN 2928 6.1/PG 2
Risk Statements 21-28-34-43
RTECS UX9625000
Safety Statements 26-28-36/37/39-45
Storage Temperature 2-8°C
Hazard Class 6.1
UN Number 2928
Packing Group 2
German water hazard class 3
GHS Pictograms GHS05
GHS Pictograms GHS06
GHS Signal Word Danger
GHS Hazard statements H300-H311-H314-H317
European Hazard Symbols Highly toxic Highly toxic (T+)
Antion Traces chloride (Cl-): ≤0.05%
Antion Traces sulfate (SO42-): ≤0.05%
Cation Traces Al: ≤0.0005%
Cation Traces Ca: ≤0.0005%
Cation Traces Cu: ≤0.0005%
Cation Traces Fe: ≤0.0005%
Cation Traces K: ≤0.005%
Cation Traces Mg: ≤0.0005%
Cation Traces Na: ≤0.005%
Cation Traces Pb: ≤0.001%
Cation Traces Zn: ≤0.0005%
Ignition Residue ≤0.1%
Impurities ≤0.001% Phosphorus (P)
Impurities ≤0.1% Insoluble matter
Purity ≥98% (HPLC)
Gene Information human ... SLC6A3(6531), SLC6A4(6532)
Boiling Point 210 °C(lit.)
Flash Point 73 °C
Flash Point 163.4 °F
Melting Point 43-46 °C(lit.)
Solubility 95% ethanol: soluble50 mg/mL, clear to slightly hazy (colorless to faint yellow)

DETAILS

Description (简体中文)
Application
用于共价修饰蛋白质的半胱氨酸残基的试剂。
Biochem/physiol Actions
使 NADP 依赖性异柠檬酸脱氢酶和许多核酸内切酶失活的巯基烷化剂。
增强来自交感神经元的原生 M 通道的电流,并作为 KCNQ2、KCNQ4 和 KCNQ5 通道的开放剂。

REFERENCES