Acemetacin

• Catalog No.: A1674
• CAS Number: 53164-05-9
• M. F.: C21H18ClNO6
• M. W.: 415.82372

SYNONYMS

• Title: 阿西美辛
• IUPAC name: 2-({2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetyl}oxy)acetic acid
• IUPAC Traditional name: acemetacin
• Synonyms: 1-(对氯苯甲酰基)-5-甲氧基-2-甲基吲哚-3-乙酸羧甲酯

DATABASE IDS

• CAS Number: 53164-05-9
• EC Number: 258-403-4
• MDL Number: MFCD00151473
• PubChem SID: 24890474

PROPERTIES

• Grade: analytical standard, for drug analysis
• GHS Signal Word: Danger
• GHS Hazard statements: H300-H310-H330
• European Hazard Symbols: Highly toxic (T+)
• Personal Protective Equipment: Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
• GHS Precautionary statements: P260-P264-P280-P284-P302 + P350-P310
• RID/ADR: UN 2811 6.1/PG 2
• Risk Statements: 26/27/28
• RTECS: NL3521400
• Safety Statements: 22-25-36/37/39-45
• Hazard Class: 6.1
• UN Number: 2811
• Packing Group: 2
• German water hazard class: 3

DETAILS

Description (简体中文)

Biochem/physiol Actions
该非甾体抗炎药 (NSAID) 专门增强蒽环类药（阿霉素、柔红霉素和 epirubium）的细胞毒性。避免 MRP 介导的多药耐药性。
Other Notes
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. A1674.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.