Hexestrol

• Catalog No.: H7753
• CAS Number: 84-16-2
• M. F.: C18H22O2
• M. W.: 270.36608
• Purity: ≥98%

SYNONYMS

• Title: 己烷雌酚
• IUPAC name: 4-[(3S,4R)-4-(4-hydroxyphenyl)hexan-3-yl]phenol
• IUPAC Traditional name: 4-[(3S,4R)-4-(4-hydroxyphenyl)hexan-3-yl]phenol
• Synonyms: 4,4′-(1,2-二乙基亚乙基)二苯酚; 二羟二苯己烷; 六羟春情素

DATABASE IDS

• Beilstein Number: 3209460
• PubChem SID: 24895805
• EC Number: 201-518-1
• MDL Number: MFCD00068996
• CAS Number: 84-16-2

PROPERTIES

• Grade: analytical standard
• Purity: ≥98%
• Gene Information: human ... ESR1(2099)rat ... Esr1(24890)
• GHS Signal Word: Danger
• GHS Hazard statements: H350
• European Hazard Symbols: Toxic (T)
• Personal Protective Equipment: Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
• GHS Precautionary statements: P201-P308 + P313
• Risk Statements: 45
• RTECS: SL0560850
• Safety Statements: 53-45
• German water hazard class: 2

DETAILS

Description (简体中文)

Biochem/physiol Actions
The carcinogen hexestrol is a nonsteroidal synthetic estrogen. Metabolic activation of hexestrol to its quinone, which reacts with DNA to form analogous depurinating adducts, may be a primary critical event leading to oncogenic mutations and cancer initiation.
Linkage
己烯雌酚的还原类似物。