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Digoxin

Catalog No. D6003 Name Sigma Aldrich
CAS Number 20830-75-5 Website http://www.sigmaaldrich.com
M. F. C41H64O14 Telephone 1-800-521-8956
M. W. 780.93846 Fax
Purity ≥95.0% (HPLC) Email
Storage Chembase ID: 104918

SYNONYMS

Title
地高辛
IUPAC name
4-[(1S,2S,5S,7R,10R,11S,14R,15S,16R)-5-{[(2R,4S,5S,6R)-5-{[(2S,4S,5S,6R)-5-{[(2S,4S,5S,6R)-4,5-dihydroxy-6-methyloxan-2-yl]oxy}-4-hydroxy-6-methyloxan-2-yl]oxy}-4-hydroxy-6-methyloxan-2-yl]oxy}-11,16-dihydroxy-2,15-dimethyltetracyclo[8.7.0.02,7.011,15]heptadecan-14-yl]-2,5-dihydrofuran-2-one
IUPAC Traditional name
digoxin
Synonyms
异羟基洋地黄毒苷

DATABASE IDS

PubChem SID 24893992
EC Number 244-068-1
Beilstein Number 77011
CAS Number 20830-75-5
MDL Number MFCD00003674

PROPERTIES

Grade analytical standard
Purity ≥95.0% (HPLC)
Gene Information human ... ABCB1(5243), CYP3A4(1576)mouse ... Abcb1a(18671), Abcb1b(18669)rat ... Atp1a1(24211)
GHS Pictograms GHS06
GHS Signal Word Danger
GHS Hazard statements H300 + H330
European Hazard Symbols Toxic Toxic (T)
Personal Protective Equipment Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
GHS Precautionary statements P260-P264-P284-P301 + P310-P310
RID/ADR UN 3462 6.1/PG 2
Risk Statements 23/25
RTECS IH6125000
Safety Statements 22-36/37/39-45
Hazard Class 6.1
UN Number 3462
Packing Group 2
German water hazard class 3

DETAILS

Description (简体中文)
包装
1, 5 g in glass bottle
100 mg in glass bottle
Biochem/physiol Actions
一种强心苷,P-糖蛋白的底物,上调 Pgp 表达和下调 SXR(固醇类异生物受体)。

REFERENCES