Daptomycin

• Catalog No.: Daptomycin
• CAS Number: 103060-53-3
• M. F.: C72H101N17O26
• M. W.: 1620.67064

SYNONYMS

• IUPAC name: (3S)-3-{[(3S,6S,9R,15S,18R,21S,24S)-3-[2-(2-aminophenyl)-2-oxoethyl]-24-(3-aminopropyl)-15,21-bis(carboxymethyl)-6-(1-carboxypropan-2-yl)-9-(hydroxymethyl)-18,31-dimethyl-2,5,8,11,14,17,20,23,26,29-decaoxo-1-oxa-4,7,10,13,16,19,22,25,28-nonaazacyclohentriacontan-30-yl]carbamoyl}-3-[(2S)-3-carbamoyl-2-[(2S)-2-decanamido-3-(1H-indol-3-yl)propanamido]propanamido]propanoic acid
• IUPAC Traditional name: daptomycin
• Brand Name: Cubicin

DATABASE IDS

• CAS Number: 103060-53-3
• CHEMBL: 508162
• Unique Ingredient Identifier: NWQ5N31VKK
• PubChem CID: 16129629
• DrugBank ID: DB00080
• Wikipedia Title: Daptomycin
• KEGG ID: D01080
• Chemspider ID: 10482098
• ATC CODE: J01XX09

PROPERTIES

• Admin Routes: Intravenous
• Bioavailability: n/a
• Excretion: Renal (78%; primarily as unchanged drug); Faeces (5.7%)
• Half Life: 7–11 hours (up to 28 hours in renal impairment)
• Legal Status: Rx-only (US)
• Metabolism: Renal (speculative)
• Pregnancy Category: B (US)
• Protein Bound: 90–95%