Rifabutin

• Catalog No.: Rifabutin
• CAS Number: 72559-06-9
• M. F.: C46H62N4O11
• M. W.: 847.00468

SYNONYMS

• IUPAC name: (7S,9Z,11S,12R,13S,14R,15R,16R,17S,18S,19Z,21Z)-2,15,17-trihydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-1'-(2-methylpropyl)-6,23,32-trioxo-8,33-dioxa-24,27,29-triazaspiro[pentacyclo[23.6.1.1^4,^7.0^5,^3^1.0^2^6,^3^0]tritriacontane-28,4'-piperidin]-1,3,5(31),9,19,21,25,29-octaen-13-yl acetate
• IUPAC Traditional name: (7S,9Z,11S,12R,13S,14R,15R,16R,17S,18S,19Z,21Z)-2,15,17-trihydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-1'-(2-methylpropyl)-6,23,32-trioxo-8,33-dioxa-24,27,29-triazaspiro[pentacyclo[23.6.1.1^4,^7.0^5,^3^1.0^2^6,^3^0]tritriacontane-28,4'-piperidin]-1,3,5(31),9,19,21,25,29-octaen-13-yl acetate
• Brand Name: Mycobutin

DATABASE IDS

• Wikipedia Title: Rifabutin
• CHEBI ID: 45367
• CAS Number: 72559-06-9
• Unique Ingredient Identifier: 1W306TDA6S
• Medline Plus: a693009
• Chemspider ID: 10482168
• DrugBank ID: DB00615
• CHEMBL: 444633
• KEGG ID: D00424
• PubChem CID: 6323490
• ATC CODE: J04AB04

PROPERTIES

• Admin Routes: Oral
• Bioavailability: 85%
• Excretion: Renal and fecal
• Half Life: 28 to 62 hours (mean)
• Legal Status: POM (UK), ?-only (U.S.)
• Metabolism: Hepatic
• Pregnancy Category: C (Australia), B (United States)
• Protein Bound: 85%