Pimecrolimus

• Catalog No.: Pimecrolimus
• CAS Number: 137071-32-0
• M. F.: C43H68ClNO11
• M. W.: 810.45312

SYNONYMS

• IUPAC name: (1R,9S,12S,13R,14S,17R,21S,23S,24R,25S,27R)-12-{1-[(1R,3R,4R)-4-chloro-3-methoxycyclohexyl]prop-1-en-2-yl}-17-ethyl-1,14-dihydroxy-23,25-dimethoxy-13,19,21,27-tetramethyl-11,28-dioxa-4-azatricyclo[22.3.1.0^4,^9]octacos-18-ene-2,3,10,16-tetrone
• IUPAC Traditional name: (1R,9S,12S,13R,14S,17R,21S,23S,24R,25S,27R)-12-{1-[(1R,3R,4R)-4-chloro-3-methoxycyclohexyl]prop-1-en-2-yl}-17-ethyl-1,14-dihydroxy-23,25-dimethoxy-13,19,21,27-tetramethyl-11,28-dioxa-4-azatricyclo[22.3.1.0^4,^9]octacos-18-ene-2,3,10,16-tetrone
• Brand Name: Elidel

DATABASE IDS

• CHEMBL: 1200686
• Chemspider ID: 10482089
• CAS Number: 137071-32-0
• DrugBank ID: DB00337
• PubChem CID: 16051947
• Unique Ingredient Identifier: 7KYV510875
• ATC CODE: D11AH02
• Wikipedia Title: Pimecrolimus

PROPERTIES

• Admin Routes: topical
• Bioavailability: low systemic absorption
• Legal Status: Rx-only (US)
• Metabolism: Hepatic CYP3A
• Pregnancy Category: C (US)
• Protein Bound: 74%–87%