Vinorelbine

• Catalog No.: Vinorelbine
• CAS Number: 71486-22-1
• M. F.: C45H54N4O8
• M. W.: 778.93226

SYNONYMS

• IUPAC name: methyl (1R,9R,10S,11R,12R,19R)-11-(acetyloxy)-12-ethyl-4-[(12S,14R)-16-ethyl-12-(methoxycarbonyl)-1,10-diazatetracyclo[12.3.1.0^3,^1^1.0^4,^9]octadeca-3(11),4,6,8,15-pentaen-12-yl]-10-hydroxy-5-methoxy-8-methyl-8,16-diazapentacyclo[10.6.1.0^1,^9.0^2,^7.0^1^6,^1^9]nonadeca-2,4,6,13-tetraene-10-carboxylate
• IUPAC Traditional name: vinorelbine
• Brand Name: Navelbine

DATABASE IDS

• Medline Plus: a695013
• CAS Number: 71486-22-1
• ATC CODE: L01CA04
• Unique Ingredient Identifier: Q6C979R91Y
• Wikipedia Title: Vinorelbine
• KEGG ID: D08680
• DrugBank ID: DB00361
• PubChem CID: 5311497
• CHEMBL: 607994
• Chemspider ID: 4470974

PROPERTIES

• Admin Routes: intravenous, oral
• Bioavailability: 43 ± 14% (oral)
• Excretion: Fecal (46%) and renal (18%)
• Half Life: 27.7 to 43.6 hours
• Legal Status: POM (UK)
• Legal Status: Rx-only (US)
• Metabolism: Hepatic (CYP3A4-mediated)
• Pregnancy Category: D (US)
• Pregnancy Category: D (Australia)
• Protein Bound: 79 to 91%