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Pimozide

Catalog No. Pimozide Name Wikipedia.org
CAS Number 2062-78-4 Website http://www.wikipedia.org/
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SYNONYMS

IUPAC name
1-{1-[4,4-bis(4-fluorophenyl)butyl]piperidin-4-yl}-2,3-dihydro-1H-1,3-benzodiazol-2-one
IUPAC Traditional name
pimozide
Brand Name
Orap

DATABASE IDS

Chemspider ID 15520
ATC CODE N05AG02
CAS Number 2062-78-4
Medline Plus a686018
CHEMBL 1423
Unique Ingredient Identifier 1HIZ4DL86F
IUPHAR ligand ID 90
DrugBank ID DB01100
Wikipedia Title Pimozide
KEGG ID D00560
CHEBI ID 8212
PubChem CID 16362

PROPERTIES

Admin Routes oral only
Bioavailability at least 40 to 50%
Excretion urine, and to a lesser extent in feces
Half Life 2 to 3 days (average in one study 55 hours)
Legal Status Rx-only, not a controlled narcotic
Metabolism hepatic, by cytochrome P450, isoenzymes 3A, and 1A2; metabolites are inactive
Pregnancy Category Teratogenic data in rats exist : drug should only be used when the benefit clearly exceeds the potential harm to the unborn

DETAILS

Description (English)

REFERENCES